Research question

Women who face age-related fertility decline have the option to safeguard future reproductive potential by banking oocytes or ovarian tissue. What are the methods that women prefer and what factors are important in their decision-making?

Design

Qualitative interview study, participants were recruited through monthly information sessions at a university hospital on oocyte banking, postings on social media, websites and newsletters and snowball sampling. Women had to be aged 35 years or older, single, childless and with a possible future desire for motherhood. Key concepts of the Health Belief Model were used as framework for the analyses.

Results

In total, 15 women participated in this qualitative study. For oocyte banking, they mentioned chances of success, extra time and faith in the technique and healthcare professionals as benefits. Risks for themselves or future children and costs were considered to be barriers in decision making. For ovarian tissue banking, the chances of success, the possibility of natural conception, the time investment and effect on menopausal symptoms were seen as benefits, and lack of experience and lack of information were considered barriers for themselves or their future children. Overall, they considered the procedures involved in oocyte banking as relatively ‘easy’, whereas ovarian tissue banking was seen as a more invasive procedure.

Conclusion

Most women preferred oocyte banking over ovarian tissue banking because of its relative convenience. Future quantitative research in a larger cohort is necessary to confirm the findings and provide more insight into the relative importance of the different factors influencing women's decision.

中文翻译：

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卵母细胞或卵巢组织库：面对年龄相关的生育能力下降的35岁以上女性的决策。

研究问题

面对与年龄有关的生育能力下降的妇女，可以选择通过卵母细胞或卵巢组织来保护未来的生殖潜力。妇女喜欢哪种方法，哪些因素对她们的决策至关重要？

设计

定性访谈研究是通过在大学医院的卵母细胞库每月信息发布会，社交媒体上的帖子，网站和新闻通讯以及雪球采样来招募参与者的。妇女必须年满35岁或以上，单身，无子女，并且将来可能希望成为母亲。健康信念模型的关键概念被用作分析的框架。

结果

总共有15名妇女参加了这项定性研究。对于卵母细胞库，他们提到成功的机会，额外的时间和对技术的信任以及医疗保健专业人员的好处。他们自己或未来孩子的风险和成本被认为是决策的障碍。对于卵巢组织库而言，成功的机会，自然受孕的可能性，时间的投入以及对更年期症状的影响被认为是有益的，而缺乏经验和信息的缺乏则被视为自身或未来子女的障碍。总的来说，他们认为卵母细胞库涉及的程序相对“容易”，而卵巢组织库被认为是一种更具侵入性的程序。

结论

由于其相对方便，大多数女性更喜欢卵母细胞储存而不是卵巢组织储存。有必要在更大的队列中进行未来的定量研究，以确认研究结果并提供更多洞察影响妇女决策的不同因素的相对重要性。