2,3-Butadienes have become valuable building blocks in the synthesis of various heterocyclic compounds. The Pd-catalyzed cross-coupling and cyclization reaction of N-(2,3-butadienyl)carboxamide of isopimaric acid with fluorine-substituted 2-iodophenols proceeds with the formation of optically active fluorinated benzofuran and benzopyrane derivatives of isopimaric acid. This transformation opens a potential route to the synthesis of hybrid compounds containing a tricyclic diterpenoid moiety and several fluorinated benzoannelated heterocycles.

中文翻译：

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包含三环二萜和氟取代杂环的杂化化合物的简便方法

2,3-丁二烯已成为各种杂环化合物合成中的重要组成部分。异戊二酸的N-（2,3-丁二烯基）羧酰胺与氟取代的2-碘苯酚的Pd催化交叉偶联和环化反应会导致形成光学活性的异戊二酸氟化苯并呋喃和苯并吡喃衍生物。这种转变为合成包含三环二萜类化合物部分和几个氟化苯甲酰化杂环的化合物开辟了一条可能的途径。