Abstract

A kind of smart calcium alginate fiber having pH indicating properties was proposed to monitor wound healing. The smart calcium alginate fiber was prepared by dyeing the hydroxypropyl trimethyl ammonium chloride chitosan (HACC) modified calcium alginate fiber with alizarin dye and anthocyanin dye, respectively. It was worth noting that modification of calcium alginate fibers with HACC enhanced the dyeing and antibacterial properties, simultaneously. When the concentration of HACC was 10 g/L, the modified calcium alginate fiber had the best dyeing performance. At the same time, the dyeing process had no significant influence on the mechanical properties of the fibers with the strength loss only around 0.2 cN/dtex. The smart calcium alginate fibers exhibited a rapid and significant color change and reversible color response at pH 2–11. Moreover, the color change could be easily observed by naked eye. Therefore, the prepared calcium alginate fibers could be a good candidate for intelligent wound dressings for visual monitoring of wound healing.

Graphic abstract

中文翻译：

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基于藻酸钙纤维和天然染料的智能pH响应柔性传感器，用于伤口愈合监测

摘要

提出了一种具有pH指示性能的智能海藻酸钙纤维来监测伤口愈合。通过分别用茜素染料和花青素染料将羟丙基三甲基氯化铵壳聚糖（HACC）改性的藻酸钙纤维染色来制备智能藻酸钙纤维。值得注意的是，用HACC修饰藻酸钙纤维可同时增强染色和抗菌性能。当HACC浓度为10 g / L时，改性海藻酸钙纤维的染色性能最佳。同时，染色过程对纤维的机械性能没有显着影响，强度损失仅为0.2 cN / dtex左右。精巧的藻酸钙纤维在pH 2-11时显示出快速且显着的颜色变化和可逆的颜色响应。此外，用肉眼很容易观察到颜色变化。因此，制备的海藻酸钙纤维可能是用于视觉伤口愈合监测的智能伤口敷料的良好候选者。

图形摘要