STUDY OBJECTIVE To determine the role of pharmacist in identifying the frequency of errors in total parenteral nutrition prescriptions in cancer patients for the years 2015 and 2016. Total parenteral nutrition has a high potential for medical errors because of its complex composition, thus leading to severe complications. Pharmacist review of the prescriptions reduces the risk of inappropriate prescribing, preparation, and administration of parenteral nutrition. METHODOLOGY An observational study was performed by collecting data of total parenteral nutrition prescriptions of 71 patients for the last two years from Pharmacy Department of specialized cancer care hospital. RESULTS It was found that the frequency of dosing errors and incomplete prescriptions was higher in 2015 compared to 2016. Additionally, the frequency of macro and micronutrients dosing errors were higher in adults (23.4% and 66.2%) compared to pediatrics (14.6% and 46.6%). Furthermore, the frequency of illegible prescriptions was higher (5.03%) in year 2016 as compared to year 2015 (1.64%). Nevertheless, such dose interventions improved patient's weight (20%) and promoted enteral feeding (42.3%). Major complication was hypophosphatemia (39.4%) followed by hyperglycemia (10%) and catheter-induced infection, i.e. sepsis (4.2%). CONCLUSION In conclusion, data suggested that pharmacist played instrumental role in identifying and rectifying total parenteral nutrition dosing errors for both micronutrients and macronutrients-with higher frequency in 2015 compared to 2016, leading to improvements in total parenteral nutrition-related complications and switches to enteral feeding.

中文翻译：

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拉合尔一家专门的癌症护理医院的总肠胃外营养处方剂量错误：临床药剂师的作用。

研究目的确定药剂师在确定2015年和2016年癌症患者肠胃外营养处方总错误率中的作用。由于肠胃外营养成分复杂，因此存在医疗错误的高可能性，从而导致严重并发症。药剂师对处方的审查减少了不适当的处方，制备和肠胃外营养管理的风险。方法：通过收集专门癌症治疗医院药房的最近两年71例患者的总肠胃外营养处方数据，进行了一项观察性研究。结果发现与2015年相比，2015年用药错误和不完整处方的发生频率更高。此外，与儿科（14.6％和46.6％）相比，成年人（23.4％和66.2％）的宏观和微量营养素剂量错误发生率更高。此外，与2015年（1.64％）相比，2016年难以辨认的处方频率更高（5.03％）。然而，这种剂量干预改善了患者的体重（20％）并促进了肠内喂养（42.3％）。主要并发症为低磷血症（39.4％），其次是高血糖（10％）和导管诱发的感染，即败血症（4.2％）。结论总之，数据表明，药剂师在识别和纠正微量营养素和大量营养素的总肠胃外营养剂量错误中发挥了作用-与2016年相比，2015年的发生频率更高，从而改善了与总肠胃外营养相关的并发症并转向了肠内喂养。