Vascular calcification (VC) is an important promoter of cardiovascular disease (CVD) in patients undergoing peritoneal dialysis (PD). Several indices can be used to evaluate VC, including the abdominal aortic calcification index (AACI) and carotid artery intima-media thickness (IMT); however, simpler and lesser expensive predictors, such as the radial augmentation index (RAI), should be investigated. A total of 101 patients undergoing PD were recruited to measure RAI, AACI, and carotid artery IMT and perform echocardiography. Fifty healthy controls (HCs) were recruited to undergo RAI measurement. RAI in patients undergoing PD was significantly higher than the RAI in HCs (86.25%±8.39% vs. 76.05%±9.81%, p < 0.05). Patients undergoing PD and who suffer with diabetic mellitus, hypertension, and CVD had more severe VC than those without the abovementioned diseases. In patients with PD, RAI was positively correlated with AACI (r = 0.671, p < 0.05) and carotid artery IMT (r = 0.596, p < 0.05). RAI was positively correlated with left ventricular end-diastolic dimensions (LVDd; r = 0.678, p < 0.05), left ventricular mass index (r = 0.595, p < 0.05), and negatively correlated with early-diastolic mitral inflow velocity/late-diastolic mitral inflow velocity (r = -0.342, p < 0.05) and left ventricular ejection fraction (r= -0.497, p < 0.05). Multiple linear regression analysis showed that RAI was associated with AACI, LVDd, age, and serum phosphate (p < 0.05). RAI might be an effective predictor of VC and cardiac structural/functional abnormalities in patients undergoing PD.

中文翻译：

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桡动脉增强指数可能是腹膜透析患者血管钙化的有效预测指标。

血管钙化（VC）是腹膜透析（PD）患者心血管疾病（CVD）的重要促进因素。评价VC的指标有腹主动脉钙化指数（AACI）、颈动脉内膜中层厚度（IMT）等；然而，应该研究更简单、更便宜的预测因子，例如径向增强指数（RAI）。总共招募了 101 名接受 PD 的患者来测量 RAI、AACI 和颈动脉 IMT 并进行超声心动图检查。招募 50 名健康对照 (HC) 进行 RAI 测量。接受 PD 的患者的 RAI 显着高于 HC 患者的 RAI（86.25%±8.39% vs. 76.05%±9.81%，p < 0.05）。患有PD且患有糖尿病、高血压和CVD的患者比没有上述疾病的患者有更严重的VC。在 PD 患者中，RAI 与 AACI（r = 0.671，p < 0.05）和颈动脉 IMT（r = 0.596，p < 0.05）呈正相关。RAI 与左心室舒张末期尺寸（LVDd；r = 0.678，p < 0.05）、左心室质量指数（r = 0.595，p < 0.05）呈正相关，与舒张早期二尖瓣流入速度/晚期呈负相关。舒张期二尖瓣流入速度（r = -0.342，p < 0.05）和左心室射血分数（r = -0.497，p < 0.05）。多元线性回归分析显示，RAI 与 AACI、LVDd、年龄和血清磷酸盐相关（p < 0.05）。RAI 可能是 PD 患者 VC 和心脏结构/功能异常的有效预测因子。