ABSTRACT

Throughout the world, more than six billion people consume milk and milk products yearly. The safety and quality of dairy milk are regularly monitored in most countries worldwide. The Israeli monitoring program of chemical residues in milk has not changed in the last decades, focusing only on major veterinary drugs and few selected environmental contaminants such as heavy metals and persistent organic pollutants. Consequently, a knowledge gap exists regarding the potential occurrence of other chemicals such as human pharmaceuticals and non-monitored pesticides in milk. In this survey, 51 commercial bovine and goat milk samples were analysed by LC-MS/MS and pharmaceutical and pesticide residues are reported in the range of 0.1–93 µg/L. Israeli milk samples revealed at least one and up to five chemical residues simultaneously. The pesticides found in milk were below the European maximum residue limit values. The risk assessment performed, indicated negligible risk.

摘要

全世界每年有超过60亿人消费牛奶和奶制品。全世界大多数国家/地区都定期监控乳汁的安全性和质量。在过去的几十年中，以色列对牛奶中化学残留物的监测计划没有改变，仅集中于主要的兽药和极少数选定的环境污染物，例如重金属和持久性有机污染物。因此，在牛奶中可能存在其他化学物质（如人类药物和非监控农药）的知识空白。在本次调查中，通过LC-MS / MS分析了51种商业牛乳和山羊乳样品，据报道药物和农药残留量为0.1–93 µg / L。以色列牛奶样品同时显示出至少一种和多达五个化学残留物。牛奶中发现的农药低于欧洲最大残留限量值。进行的风险评估表明风险可忽略不计。