During training in a novel dynamic environment, the non-dominant upper limb favors feedback control, whereas the dominant limb favors feedforward mechanisms. Early somatosensory evoked potentials (SEPs) offer a means to explore differences in cortical regions involved in sensorimotor integration (SMI). This study sought to compare differences in SMI between the right (Dom) and left (Non-Dom) hand in healthy right-handed participants. SEPs were recorded in response to median nerve stimulation, at baseline and post, a motor skill acquisition-tracing task. One group (n = 12) trained with their Dom hand and the other group (n = 12), with their Non-Dom hand. The Non-Dom hand was significantly more accurate at baseline (p < 0.0001) and both groups improved with time (p < 0.0001), for task accuracy, with no significant interaction effect between groups for both post-acquisition and retention. There were significant group interactions for the N24 (p < 0.001) and the N30 (p < 0.0001) SEP peaks. Post motor acquisition, the Dom hand had a 28.9% decrease in the N24 and a 23.8% increase in the N30, with opposite directional changes for the Non-Dom hand; 22.04% increase in N24 and 24% decrease in the N30. These SEP changes reveal differences in early SMI between Dom and Non-Dom hands in response to motor acquisition, providing objective, temporally sensitive measures of differences in neural mechanisms between the limbs.

中文翻译：

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遵循一种新颖的运动追踪任务后，在显性和非显性手之间的早期体感诱发电位的差异变化。

在新颖的动态环境中进行训练时，非显性上肢有利于反馈控制，而显性上肢有利于前馈机制。早期的体感诱发电位（SEP）提供了一种探索参与感觉运动整合（SMI）的皮质区域差异的方法。这项研究旨在比较健康的右撇子参与者在右手（Dom）和左手（Non-Dom）之间的SMI差异。在基线和运动技能习得跟踪任务后，响应中位神经刺激记录SEP。一组（n = 12）用Dom手训练，另一组（n = 12）用非Dom手训练。对于任务准确度，非Dom手在基线时的准确度明显更高（p <0.0001），并且两组随时间的推移有所改善（p <0.0001），两组之间在获取后和保留方面都没有明显的交互作用。N24（p <0.001）和N30（p <0.0001）SEP峰存在显着的组间相互作用。运动后，Dom手的N24下降28.9％，N30增加23.8％，与非Dom的方向相反。N24上升22.04％，N30下降24％。这些SEP变化揭示了响应运动获取的Dom和非Dom手之间早期SMI的差异，从而提供了客观，时间敏感的四肢之间神经机制差异的度量。N24下降9％，N30增长23.8％，非Dom手的方向变化相反；N24上升22.04％，N30下降24％。这些SEP变化揭示了响应运动获取的Dom和非Dom手之间早期SMI的差异，从而提供了客观，时间敏感的四肢之间神经机制差异的度量。N24下降9％，N30增长23.8％，非Dom手的方向变化相反；N24上升22.04％，N30下降24％。这些SEP变化揭示了响应运动获取的Dom和非Dom手之间早期SMI的差异，从而提供了对肢体之间神经机制差异的客观，时间敏感的测量。