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The association between CYBA gene C242T variant and risk of metabolic syndrome.
European Journal of Clinical Investigation ( IF 4.4 ) Pub Date : 2020-05-14 , DOI: 10.1111/eci.13275
Leyla Pourgholi 1, 2 , Fatemeh Pourgholi 3 , Shayan Ziaee 1 , Hamidreza Goodarzynejad 4 , Maryam Hosseindokht 1 , Mohammadali Boroumand 1 , Ali Mandegary 2, 5
Affiliation  

Both inflammation and oxidative stress may contribute to pathogenesis of metabolic syndrome (MetS). The C242T polymorphism (rs4673) in the CYBA gene, as the main components of NAD (P) H oxidase, causes inter‐individual variability in the enzyme activity. We aimed to investigate the association between this polymorphism with MetS and its components.

中文翻译:

CYBA基因C242T变异与代谢综合征风险的相关性。

炎症和氧化应激都可能导致代谢综合征 (MetS) 的发病机制。CYBA 基因中的 C242T 多态性 (rs4673) 作为 NAD (P) H 氧化酶的主要成分,导致酶活性的个体差异。我们旨在研究这种多态性与 MetS 及其组件之间的关联。
更新日期:2020-05-14
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