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Front Cover: Metabolites from Two Dominant Thermophilic Fungal Species Thermomyces lanuginosus and Scytalidium thermophilum (C&B 5/2020)
Chemistry & Biodiversity ( IF 2.3 ) Pub Date : 2020-05-14 , DOI: 10.1002/cbdv.202000322 Xiao‐Yu Yang 1 , Jun‐Xian Zhang 1 , Qiu‐Yan Ding 1 , Zi‐Cong He 1 , Chun‐Yan Zhu 1 , Ke‐Qin Zhang 1 , Xue‐Mei Niu 1
Chemistry & Biodiversity ( IF 2.3 ) Pub Date : 2020-05-14 , DOI: 10.1002/cbdv.202000322 Xiao‐Yu Yang 1 , Jun‐Xian Zhang 1 , Qiu‐Yan Ding 1 , Zi‐Cong He 1 , Chun‐Yan Zhu 1 , Ke‐Qin Zhang 1 , Xue‐Mei Niu 1
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Two thermophilic fungi isolated from Tengchong,Thermomyces lanuginosus and Scytalidium thermophilum are among the most ubiquitous thermophilic fungi in compost and soil. Chemical study on these two prevalent strains led to isolation of 23 metabolites, including one new metabolite, therlanubutanolide (1, in red), and 15 known compounds (2 ‐ 16), isolated from the YGP culture broth of Thermomyces lanuginosus and 7 known compounds (17 ‐ 23) isolated from Scytalidium thermophilum, respectively. Therlanubutanolide (1) shared the quite similar features of the same carbon skeleton and saturation as natural hexadecanoic acids. This was for the first time reported discovery of such a lactone as natural occurring metabolite. All the compounds were reported for the first time from thermophilic fungi. A type of PKS‐derived metabolites, 3,4‐dihydronaphthalen‐1(2H)‐ones (in white) which were widely found in plant pathogenic fungi as phytotoxins and reported to have antimicrobial activity, were obtained from both dominant thermophilic fungi. The frequent occurrence of such PKS phytotoxins in these two thermophilic fungi might suggest particular ecological interest as reported by Niu et al. in their full paper at10.1002/cbdv.202000137.
中文翻译：
封面：来自两个主要嗜热真菌物种嗜热单胞菌和嗜热镰状菌的代谢产物（C＆B 5/2020）
从腾冲，嗜热嗜热菌和嗜热镰状菌中分离出的两种嗜热真菌是堆肥和土壤中最普遍的嗜热真菌。上导致的23种代谢物，包括一个新的代谢物，therlanubutanolide（隔离这两个流行株化学研究1，在红）和15种已知化合物（2 - 16），从所述YGP培养肉汤中分离细毛嗜热霉和7种已知化合物（17 - 23）从分离孢属嗜热分别。茶色丁醇（1）具有与天然十六烷酸相同的碳骨架和饱和度，具有非常相似的特征。这是首次报道发现这种内酯为天然代谢产物。所有化合物均首次报道来自嗜热真菌。从两种主要的嗜热真菌中都获得了一种由PKS衍生的代谢物3,4-dihydronaphthalen-1（2 H）-1（白色），在植物病原性真菌中作为植物毒素被广泛发现并据称具有抗菌活性。如Niu等报道，这两种嗜热真菌中PKS植物毒素的频繁发生可能暗示了其特别的生态学意义。在他们的全文中at10.1002 / cbdv.202000137。
更新日期：2020-05-14
中文翻译：
封面：来自两个主要嗜热真菌物种嗜热单胞菌和嗜热镰状菌的代谢产物（C＆B 5/2020）
从腾冲，嗜热嗜热菌和嗜热镰状菌中分离出的两种嗜热真菌是堆肥和土壤中最普遍的嗜热真菌。上导致的23种代谢物，包括一个新的代谢物，therlanubutanolide（隔离这两个流行株化学研究1，在红）和15种已知化合物（2 - 16），从所述YGP培养肉汤中分离细毛嗜热霉和7种已知化合物（17 - 23）从分离孢属嗜热分别。茶色丁醇（1）具有与天然十六烷酸相同的碳骨架和饱和度，具有非常相似的特征。这是首次报道发现这种内酯为天然代谢产物。所有化合物均首次报道来自嗜热真菌。从两种主要的嗜热真菌中都获得了一种由PKS衍生的代谢物3,4-dihydronaphthalen-1（2 H）-1（白色），在植物病原性真菌中作为植物毒素被广泛发现并据称具有抗菌活性。如Niu等报道，这两种嗜热真菌中PKS植物毒素的频繁发生可能暗示了其特别的生态学意义。在他们的全文中at10.1002 / cbdv.202000137。
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