The recent publication of a study into the contribution of embryo chromosomal abnormalities in recurrent pregnancy loss (RPL) affords the opportunity to revisit the hypothesis that women with an aneuploid pregnancy loss have a better chance of a successful pregnancy next time than women with a chromosomally normal loss. A previous miscarriage with an abnormal karyotype (unrelated to a parental chromosome rearrangement) should not be viewed as a marker of an increased likelihood of aneuploidy in a subsequent pregnancy; it is (counterintuitively) likely to be indicative of a reduced risk of clinical miscarriage (with a higher proportion of aneuploid products) and an excellent chance for the live birth of the next pregnancy. Each couple should be treated on their own merits and with appropriate investigations performed where indicated; caution should be advised regarding offering preimplantation genetic testing for aneuploidy (PGT-A).

中文翻译：

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复发性流产（RPL）的平方。

最近发表的一项关于胚胎染色体异常在反复妊娠丢失（RPL）中的贡献的研究的发表提供了一个机会，可以重新审视一种假设，即非整倍体妊娠丢失的妇女下次成功怀孕的机会比染色体正常的妇女更好。失利。先前的异常核型（与父母染色体重排无关）的流产不应被视为标志着后续妊娠中非整倍性可能性增加；（反常地），这可能表明临床流产的风险降低（非整倍体产品的比例更高），并且下次妊娠活产的机会很高。每对夫妇应根据自己的情况接受治疗，并在有指征的情况下进行适当的调查；