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Factors associated with temporal window failure in transcranial Doppler sonography.
Neurological Sciences ( IF 3.3 ) Pub Date : 2020-05-13 , DOI: 10.1007/s10072-020-04459-6
Chan-Hyuk Lee 1 , Seung-Ho Jeon 1 , Su-Jung Wang 1 , Byoung-Soo Shin 1, 2 , Hyun Goo Kang 1, 2
Affiliation  

BACKGROUND Temporal window failure (TWF) is found in 8-20% of subjects. There are still insufficient studies about the factors affecting TWF. We aimed to elucidate the underlying causes of TWF. METHODS We analyzed 376 patients who underwent both transcranial Doppler sonography and cerebral angiographic imaging. They were divided into two groups: with and without TWF. Demographics, cardiovascular factors, degree of stenosis from the proximal intracranial artery to the middle cerebral artery (MCA), MCA diameter, and skull features were examined. RESULTS The subjects were 314 TWF-negative patients and 62 TWF-positive patients. The TWF-negative group was younger than that of the TWF-positive group (67.0 ± 12.1 vs. 75.2 ± 9.4, p < 0.001). The proportion of men in the TWF-negative group was higher than in the TWF-positive group (71% vs. 29%; p < 0.001). The TWF-negative group had a higher smoking rate than the TWF-positive group (34.4% vs. 12.9%; p = 0.001). In multivariate logistic regression analysis, age (odds ratio (OR), 1.05; p = 0.019), sex (OR, 4.64; p = 0.002), temporal bone thickness (OR, 6.03; p < 0.001), temporal bone density (OR, 0.996; p = 0.002), and soft tissue thickness (OR, 1.31; p = 0.004) significantly affected TWF. CONCLUSIONS In addition to age, sex, temporal bone thickness, and temporal bone density which were previously reported as variables associated with TWF, we confirmed that soft tissue thickness of the temporal area is a new associated factor of TWF. Measuring soft tissue thickness of the temporal area for patients with suspected TWF could be useful in identifying measurement error due to technical problems.

中文翻译:

经颅多普勒超声检查中与颞窗衰竭相关的因素。

背景技术在8-20%的受试者中发现了颞窗衰竭(TWF)。关于影响TWF的因素的研究仍然不足。我们旨在阐明TWF的根本原因。方法我们分析了376例同时行经颅多普勒超声和脑血管造影检查的患者。他们分为两组:有和没有TWF。检查了人口统计学,心血管因素,从颅内近端到大脑中动脉(MCA)的狭窄程度,MCA直径和颅骨特征。结果受试者为314例TWF阴性患者和62例TWF阳性患者。TWF阴性组比TWF阳性组年轻(67.0±12.1对75.2±9.4,p <0.001)。TWF阴性组的男性比例高于TWF阳性组(71%比29%; p < 0.001)。TWF阴性组的吸烟率高于TWF阳性组(34.4%对12.9%; p = 0.001)。在多元logistic回归分析中,年龄(优势比(OR)为1.05; p = 0.019),性别(OR为4.64; p = 0.002),颞骨厚度(OR为6.03; p <0.001),颞骨密度(OR ,0.996; p = 0.002)和软组织厚度(OR,1.31; p = 0.004)显着影响TWF。结论除了以前报道为与TWF相关的变量的年龄,性别,颞骨厚度和颞骨密度外,我们证实颞部软组织厚度是TWF的新相关因素。对于疑似TWF的患者,测量颞区软组织厚度可能有助于识别由于技术问题而导致的测量误差。TWF阴性组的吸烟率高于TWF阳性组(34.4%对12.9%; p = 0.001)。在多因素logistic回归分析中,年龄(优势比(OR)为1.05; p = 0.019),性别(OR为4.64; p = 0.002),颞骨厚度(OR为6.03; p <0.001),颞骨密度(OR ,0.996; p = 0.002)和软组织厚度(OR,1.31; p = 0.004)显着影响TWF。结论除了以前报道为与TWF相关的变量的年龄,性别,颞骨厚度和颞骨密度外,我们证实颞部软组织厚度是TWF的新相关因素。对于疑似TWF的患者,测量颞区软组织厚度可能有助于识别由于技术问题而导致的测量误差。TWF阴性组的吸烟率高于TWF阳性组(34.4%对12.9%; p = 0.001)。在多元logistic回归分析中,年龄(优势比(OR)为1.05; p = 0.019),性别(OR为4.64; p = 0.002),颞骨厚度(OR为6.03; p <0.001),颞骨密度(OR ,0.996; p = 0.002)和软组织厚度(OR,1.31; p = 0.004)显着影响TWF。结论除了以前报道为与TWF相关的变量的年龄,性别,颞骨厚度和颞骨密度外,我们证实颞部软组织厚度是TWF的新相关因素。对于疑似TWF的患者,测量颞区软组织厚度可能有助于识别由于技术问题而导致的测量误差。p = 0.001)。在多元logistic回归分析中,年龄(优势比(OR)为1.05; p = 0.019),性别(OR为4.64; p = 0.002),颞骨厚度(OR为6.03; p <0.001),颞骨密度(OR ,0.996; p = 0.002)和软组织厚度(OR,1.31; p = 0.004)显着影响TWF。结论除了以前报道为与TWF相关的变量的年龄,性别,颞骨厚度和颞骨密度外,我们证实颞部软组织厚度是TWF的新相关因素。对于疑似TWF的患者,测量颞区软组织厚度可能有助于识别由于技术问题而导致的测量误差。p = 0.001)。在多元logistic回归分析中,年龄(优势比(OR)为1.05; p = 0.019),性别(OR为4.64; p = 0.002),颞骨厚度(OR为6.03; p <0.001),颞骨密度(OR ,0.996; p = 0.002)和软组织厚度(OR,1.31; p = 0.004)显着影响TWF。结论除了以前报道为与TWF相关的变量的年龄,性别,颞骨厚度和颞骨密度外,我们证实颞部软组织厚度是TWF的新相关因素。对于疑似TWF的患者,测量颞区软组织厚度可能有助于识别由于技术问题而导致的测量误差。6.03;p <0.001),颞骨密度(OR,0.996; p = 0.002)和软组织厚度(OR,1.31; p = 0.004)显着影响TWF。结论除了以前报道为与TWF相关的变量的年龄,性别,颞骨厚度和颞骨密度外,我们证实颞部软组织厚度是TWF的新相关因素。对于疑似TWF的患者,测量颞区软组织厚度可能有助于识别由于技术问题而导致的测量误差。6.03;p <0.001),颞骨密度(OR,0.996; p = 0.002)和软组织厚度(OR,1.31; p = 0.004)显着影响TWF。结论除了以前报道为与TWF相关的变量的年龄,性别,颞骨厚度和颞骨密度外,我们证实颞部软组织厚度是TWF的新相关因素。对于疑似TWF的患者,测量颞区软组织厚度可能有助于识别由于技术问题而导致的测量误差。我们证实颞骨软组织厚度是TWF的新的相关因素。对于疑似TWF的患者,测量颞区软组织厚度可能有助于识别由于技术问题而导致的测量误差。我们证实颞叶区域的软组织厚度是TWF的新的相关因素。对于疑似TWF的患者,测量颞区软组织厚度可能有助于识别由于技术问题而导致的测量误差。
更新日期:2020-05-13
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