Osteosarcoma is a rare tumor diagnosed at any age; however younger age is a common risk factor. In addition, multiple factors are believed to contribute to higher rates of osteosarcoma, particularly race and gender. Although diagnosed worldwide, osteosarcoma is found to be more prevalent in Africa with high numbers of cases reported in Nigeria, Uganda, and Sudan. Additionally, higher rates are detected in African Americans, suggesting a genetic predisposition linked to race. This review focuses on identifying high risk factors of osteosarcoma with an emphasis on sarcoma epidemiology and risk factors in African countries.

中文翻译：

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骨肉瘤的流行病学和危险因素。

骨肉瘤是一种在任何年龄均可诊断的罕见肿瘤。但是，年龄较小是常见的危险因素。另外，相信多种因素导致骨肉瘤的发病率升高，特别是种族和性别。尽管骨肉瘤在世界范围内得到诊断，但发现它在非洲更为普遍，尼日利亚，乌干达和苏丹报告了许多病例。此外，在非裔美国人中检出率更高，表明与种族有关的遗传易感性。这篇综述的重点是确定骨肉瘤的高危因素，重点是非洲国家的肉瘤流行病学和危险因素。