Abstract

A novel oxime polyketide, maydisone (1), along with two known compounds, 7-hydroxy-2,5-dimethylchromone (2) and 2,5-dimethylbenzoic acid (3) were isolated from the cultures of Bipolaris maydis. Their structures were identified by the application of NMR and MS data analyses and comparison with previous reports. Compound 1 showed the most powerful inhibition of α-glucosidase, with an IC₅₀ value of 68.30 ± 0.83 µM.

中文翻译：

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Maydisone，一种来自 Bipolaris maydis 培养物的新型肟聚酮化合物

摘要

从Bipolaris maydis的培养物中分离出一种新的肟聚酮化合物，maydisone ( 1 )，以及两种已知的化合物，7-羟基-2,5-二甲基色酮 ( 2 ) 和 2,5-二甲基苯甲酸 ( 3 ) 。它们的结构是通过应用 NMR 和 MS 数据分析并与以前的报告进行比较来确定的。化合物1对α-葡萄糖苷酶的抑制作用最强，IC ₅₀值为 68.30 ± 0.83 µM。