Human scalp hair is a biological matrix that can trap chemical vapours from explosives (TNT), drugs (THC) and chemical weapons (yperite). The external contamination of human's hair following exposure to organophosphorus (OP) nerve agent was simulated by model compounds: triethyl phosphate (TEP) and diisopropyl fluorophosphate (DFP). In this work were exposed strands of hair to vapours of TEP and DFP (3 and 7 ppm_v) to model sorption kinetics. Sorption isotherms were also investigated at several contamination levels (80–3000 mg min.m⁻³). OP nerve agent simulants were extracted from hair by soaking in DCM. Raw extracts were analysed in GC-MS/MS to quantify each simulant content in hair. Results were fitted by applying isotherm or kinetic equations. The best model was found to be bimodal first-order, suggesting the co-existence of two different mechanisms of sorption. The best equation to describe OP vapours incorporation on hair was Freundlich model. Thus hair can be used as a passive sensor able to trap chemical G-agents and can also offer valuable information regarding both individual contamination and proof of exposure to chemical weapons.

人头皮的头发是一种生物基质，可以捕获炸药（TNT），毒品（THC）和化学武器（钇铁矿）中的化学蒸气。暴露于有机磷（OP）神经毒剂后人发的外部污染是通过以下模型化合物模拟的：磷酸三乙酯（TEP）和氟磷酸二异丙酯（DFP）。在这项工作中，将头发束暴露于TEP和DFP蒸气（3和7 ppm _v）中，以模拟吸附动力学。还研究了几种污染水平下的吸附等温线（最低80-3000 mg.m ^-3）。通过浸入DCM从头发中提取OP神经毒剂模拟物。在GC-MS / MS中分析原始提取物，以量化头发中每种模拟物的含量。通过应用等温线或动力学方程拟合结果。发现最好的模型是双峰一阶模型，表明两种不同的吸附机制并存。描述OP蒸气结合在头发上的最佳方程式是Freundlich模型。因此，头发可以用作能够捕获化学G剂的被动传感器，也可以提供有关个人污染和化学武器暴露证据的有价值的信息。