The value of thyroid scintigraphy in hyperthyroidism diagnosis has long been the subject of debate. Unresolved issue is whether scintigraphy should be performed routinely, selectively, or for all hyperthyroidism patients. So, this study is concerned with the evaluation of thyroid scintigraphy for identifying hyperthyroidism in comparison with thyroid stimulating hormone (TSH) and ultrasound. This is cross sectional study including convenient patients sample (n = 50, 15 males and 35 females) aged (20–50 years) with primary hyperthyroidism and were attending endocrine clinics at King Faisal Specialist Hospital and Research Centre. All patients performed clinical investigations (TSH, ultrasound and thyroid scintigraphy). Among these patients, 96%, 48/50, had positive findings for hyperthyroidism with thyroid SC (95% CI; 96.0–99.5%); 84%, 42/50, had positive findings for hyperthyroidism by US (95% CI; 70.9–92.8%); and 56%, 28/50, had positive findings for hyperthyroidism by TSH measurement (95% CI; 41.3.0–70.0%). There was very good agreement between scintigraphy diagnosis and ultrasonography (kappa score = 0.812 (P < 0.0001), 95% CI (0.77–0.85). In many cases, scintigraphy provides considerably more functioning and anatomic details than ultrasound. In conclusion, these findings bring forth practical aspects of thyroid scintigraphy utilization for hyperthyroidism. By combining functional and anatomical information in one step, scintigraphy provides non-invasive, simple, fast and cost effective hyperthyroidism diagnostic method and has the potential to replace TSH and ultrasonography in hyperthyroidism investigation.

甲状腺闪烁显像在甲亢诊断中的价值长期以来一直是争论的话题。未解决的问题是是否应常规，选择性或所有甲亢患者进行闪烁显像。因此，与甲状腺刺激素（TSH）和超声检查相比，这项研究与评估甲状腺闪烁显像术以确定甲状腺功能亢进有关。这是一项横断面研究，包括年龄在20至50岁之间的原发性甲亢的方便患者样本（n = 50，男15，女35），并在费萨尔国王专科医院和研究中心就诊于内分泌诊所。所有患者均进行了临床检查（TSH，超声和甲状腺闪烁显像）。在这些患者中，有96％（48/50）的甲状腺功能亢进合并甲状腺SC阳性（95％CI； 96.0-99.5％）；84％，42/50，美国甲状腺功能亢进阳性（95％CI； 70.9–92.8％）；通过TSH测量，有56％的甲状腺功能亢进阳性（28/50）（95％CI； 41.3.0-70.0％）。闪烁显像诊断与超声检查之间有很好的一致性（kappa评分= 0.812（P  <0.0001），95％CI（0.77–0.85）。在许多情况下，闪烁显像比超声能提供更多的功能和解剖学细节。总之，这些发现提出了利用甲状腺闪烁显像术治疗甲亢的实用方面。通过一步一步结合功能和解剖学信息，闪烁显像技术可提供非侵入性，简单，快速且经济高效的甲状腺功能亢进症诊断方法，并有可能在甲状腺功能亢进症研究中取代TSH和超声检查。