Abstract Gold nanoparticles (AuNPs) synthesized via laser ablation technique were incorporated into polymeric blend of Chitosan (CS)/Polyvinyl Alcohol (PVA) in different contents via controlling the time of ablation. The prepared films were studied via XRD and FTIR. Moreover, microstructural and morphological behaviors were investigated. The AuNPs were formed as spherical shapes scattered through the polymeric blend with diameters around 20 nm composition prepared at ablation time of 10.0 min. In addition, the crystallinity of the composition was enhanced significantly with AuNPs contribution. The antibacterial activity was examined under visible light to show the effect of AuNPs. The inhibition zones have grown from 4.2 ± 0.9 mm to be 13.1 ± 1.3 mm against E. coli and from 6.4 ± 1.2 mm to be 24.8 ± 2.4 mm against S. aureus for the lowest and the highest contributions of AuNPs respectively. This significant enhancement of the antibacterial activity of AuNPs scattered through biopolymer could suggest these compositions for more investigations in biomedical applications such as wound dressing and disinfection.

中文翻译：

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纳秒激光烧蚀制备纳米金包埋壳聚糖/聚乙烯醇的伤口愈合活性

摘要 通过控制烧蚀时间，将激光烧蚀技术合成的金纳米粒子（AuNPs）掺入不同含量的壳聚糖（CS）/聚乙烯醇（PVA）聚合物混合物中。通过XRD和FTIR研究制备的薄膜。此外，研究了微观结构和形态行为。AuNPs 形成为球形形状，散布在直径约 20 nm 的聚合物混合物中，在 10.0 分钟的消融时间制备。此外，AuNPs 的贡献显着提高了组合物的结晶度。在可见光下检查抗菌活性以显示 AuNPs 的效果。抑菌圈从 4.2 ± 0.9 mm 增加到 13.1 ± 1.3 mm 对大肠杆菌和从 6.4 ± 1.2 mm 到 24.8 ± 2.4 mm 对 S。aureus 分别代表 AuNPs 的最低和最高贡献。分散在生物聚合物中的 AuNP 抗菌活性的显着增强表明这些组合物可用于在生物医学应用（如伤口敷料和消毒）中进行更多研究。