Abstract Quorum quenching (QQ) is a new and promising strategy that disrupts the quorum sensing system, a universal and important microbial communication that results in membrane biofouling and other various communal behaviors. A bacterial strain Z4 with a relatively high QQ ability was isolated from a wastewater treatment plant and identified as a Serratia sp. This is the first report of a bacterium belonging to the genus Serratia with such QQ ability. This strain not only degraded at least 93% of 10 μg/ml C8-HSL signaling molecules within 24 h, but also reduced the main bacterial by-products in sludge mixture, soluble microbial products (SMP) mass by 75%, and extracellular polymeric substances (EPS) by 37%, during wastewater treatment. Interestingly, the presence of strain Z4 in the sludge had an obvious impact on the microbial diversity of the sludge mixture during wastewater treatment. The results show that the isolated strain Z4 is a very potent strain for use in a QQ strategy, and the application and mechanism in biofouling mitigation should be further explored.

中文翻译：

---

土著群体淬灭细菌的特征及其对污水处理过程中污泥混合物的 SMP、EPS 和微生物群落的影响

摘要 群体淬灭 (QQ) 是一种新的、有前途的策略，它可以破坏群体感应系统，这是一种普遍且重要的微生物通讯，可导致膜生物污染和其他各种公共行为。从污水处理厂中分离出一株具有较高QQ能力的菌株Z4，鉴定为沙雷氏菌属。这是具有这种QQ能力的沙雷氏菌属细菌的首次报道。该菌株不仅在 24 小时内降解了至少 93% 的 10 μg/ml C8-HSL 信号分子，而且还减少了污泥混合物中的主要细菌副产物、可溶性微生物产物 (SMP) 质量 75% 和细胞外聚合物在废水处理过程中，物质 (EPS) 减少了 37%。有趣的是，污泥中Z4菌株的存在对污水处理过程中污泥混合物的微生物多样性有明显影响。结果表明，分离菌株Z4是用于QQ策略的非常有效的菌株，应进一步探索其在生物污染缓解中的应用和机制。