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Finding Their Type: Elusive Antigenic Sites on Dengue Virus 3 Mapped with Human Antibodies.
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2020-05-13 , DOI: 10.1016/j.chom.2020.04.015
Vanessa V Sarathy 1 , Alan D T Barrett 1
Affiliation  

In this issue of Cell Host & Microbe, Young et al. shed light on dengue virus 3-specific epitopes. Mapping of human monoclonal antibodies led to the discovery of six quaternary antigenic sites with strong neutralizing activity suggesting that epitopes involved with protective immunity may be more complex than previously realized.

中文翻译:

找到它们的类型:登革热病毒3映射人类抗体的难以捉摸的抗原位点。

在本期《细胞宿主与微生物》中,Young等人。阐明了登革热病毒3特异性表位。人单克隆抗体的定位导致发现了具有强中和活性的六个季抗原位点,这表明涉及保护性免疫的表位可能比以前意识到的更为复杂。
更新日期:2020-05-13
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