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Hold It Right There! Gonococci Preserve Epithelium Integrity during Intimate Adherence.
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2020-05-13 , DOI: 10.1016/j.chom.2020.04.020 Joseph P Dillard 1
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2020-05-13 , DOI: 10.1016/j.chom.2020.04.020 Joseph P Dillard 1
Affiliation
Exfoliation is used as a mechanism to remove bacterially infected cells from the body. In this issue of Cell Host & Microbe, Muenzner and Hauck (2020) find that Neisseria gonorrhoeae blocks exfoliation by producing nitric oxide at the bacterial-host cell interface to promote tissue integrity. Uropathogenic Escherichia coli stimulates the same pathway, suggesting a common mechanism among bacterial pathogens.
中文翻译:
坚持在那里!淋球菌在亲密附着过程中保持上皮完整性。
剥脱被用作从体内去除细菌感染细胞的机制。在本期《细胞宿主与微生物》中,Muenzner和Hauck(2020)发现淋病奈瑟氏球菌通过在细菌-宿主细胞界面产生一氧化氮来促进组织完整性,从而阻止脱落。致病性大肠埃希氏菌刺激相同的途径,提示细菌病原体共有机制。
更新日期:2020-05-13
中文翻译:
坚持在那里!淋球菌在亲密附着过程中保持上皮完整性。
剥脱被用作从体内去除细菌感染细胞的机制。在本期《细胞宿主与微生物》中,Muenzner和Hauck(2020)发现淋病奈瑟氏球菌通过在细菌-宿主细胞界面产生一氧化氮来促进组织完整性,从而阻止脱落。致病性大肠埃希氏菌刺激相同的途径,提示细菌病原体共有机制。