The rapid emergence of a highly pathogenic, readily transmissible coronavirus has resulted in a global pandemic, affecting millions and destabilizing economies. This catastrophe triggered a clarion call for the immediate deployment of a protective vaccine. We describe the unique challenges of developing a vaccine against SARS-CoV-2 in a pandemic setting.

中文翻译：

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大流行期间针对新病毒的疫苗开发面临的挑战。


高致病性、易传播的冠状病毒的迅速出现已导致全球大流行，影响数百万人并破坏经济稳定。这场灾难引发了立即部署保护性疫苗的号角。我们描述了在大流行背景下开发针对 SARS-CoV-2 疫苗的独特挑战。