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Whole-genome sequence of a reassortant G9P[4] rotavirus A strain from two children in the Czech Republic.
Archives of Virology ( IF 2.5 ) Pub Date : 2020-05-13 , DOI: 10.1007/s00705-020-04648-w
Romana Moutelíková 1 , Pavel Sauer 2 , Jana Prodělalová 1
Affiliation  

An unusual reassortant rotavirus A (RVA) strain was isolated during RVA surveillance in two previously hospitalized children in 2018. G/P typing revealed uncommon G9P[4] genotypes, so the strains were further characterized by Illumina next-generation sequencing. Whole-genome typing showed that the two strains had a DS-1-like backbone except for NSP2: G9-P[4]-I2-R2-C2-M2-A2-N1-T2-E2-H2. The two strains shared 99.9-100% nucleotide sequence identity in all genes.

中文翻译:

来自捷克共和国两名儿童的重配 G9P[4] 轮状病毒 A 株的全基因组序列。

2018 年,在对两名先前住院的儿童进行 RVA 监测期间,分离出了一种不寻常的重配轮状病毒 A (RVA) 株。G/P 分型揭示了不常见的 G9P[4] 基因型,因此通过 Illumina 新一代测序对这些株进行了进一步表征。全基因组分型显示,除了NSP2外,这两个菌株均具有类似DS-1的主链:G9-P[4]-I2-R2-C2-M2-A2-N1-T2-E2-H2。两个菌株的所有基因具有 99.9-100% 的核苷酸序列同一性。
更新日期:2020-05-13
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