SUMMARYAntimicrobial-resistant ESKAPE ( Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) pathogens represent a global threat to human health. The acquisition of antimicrobial resistance genes by ESKAPE pathogens has reduced the treatment options for serious infections, increased the burden of disease, and increased death rates due to treatment failure and requires a coordinated global response for antimicrobial resistance surveillance. This looming health threat has restimulated interest in the development of new antimicrobial therapies, has demanded the need for better patient care, and has facilitated heightened governance over stewardship practices.

中文翻译：

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ESKAPE 病原体的抗菌素耐药性。


摘要耐药性 ESKAPE（屎肠球菌、金黄色葡萄球菌、肺炎克雷伯菌、鲍曼不动杆菌、铜绿假单胞菌和肠杆菌属）病原体对人类健康构成全球性威胁。 ESKAPE 病原体获得抗菌素耐药性基因减少了严重感染的治疗选择，增加了疾病负担，并因治疗失败而增加了死亡率，需要全球协调应对抗菌素耐药性监测。这种迫在眉睫的健康威胁重新激发了人们对开发新抗菌疗法的兴趣，要求需要更好的患者护理，并促进了对管理实践的加强治理。