SUMMARYAntimicrobial-resistant ESKAPE ( Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) pathogens represent a global threat to human health. The acquisition of antimicrobial resistance genes by ESKAPE pathogens has reduced the treatment options for serious infections, increased the burden of disease, and increased death rates due to treatment failure and requires a coordinated global response for antimicrobial resistance surveillance. This looming health threat has restimulated interest in the development of new antimicrobial therapies, has demanded the need for better patient care, and has facilitated heightened governance over stewardship practices.

中文翻译：

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ESKAPE病原体中的抗菌素耐药性。

小结耐药性ESKAPE（粪肠球菌，金黄色葡萄球菌，肺炎克雷伯菌，鲍曼不动杆菌，铜绿假单胞菌和肠杆菌属）病原体对人类健康构成了全球威胁。ESKAPE病原体获得的抗药性基因减少了严重感染的治疗选择，增加了疾病负担，并由于治疗失败而增加了死亡率，因此需要对抗药性监测采取协调一致的全球应对措施。这种迫在眉睫的健康威胁重新激发了人们对开发新的抗微生物疗法的兴趣，要求对患者进行更好的护理，并促进了对管理方法的加强治理。