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The Warburg hypothesis and weak ELF biointeractions
Electromagnetic Biology and Medicine ( IF 1.6 ) Pub Date : 2020-03-12 , DOI: 10.1080/15368378.2020.1737810
Abraham R Liboff 1
Affiliation  

ABSTRACT The Warburg observation concerning ATP generation in cancer cells is analyzed with regard to the likely involvement of H+ resonance effects on the angular velocity of the ATP synthase rotor. It is reasonable to expect that the variety of diseases associated with mitochondrial dysfunction may in part be related to the ATP synthase rate of rotation. Experimental measurements of ATP synthase rotational rates, as found in the literature, are consistent with what might be expected from the ion cyclotron resonance (ICR) frequencies of protons moving under a Lorentz force determined by the approximate surface intensity of the geomagnetic field (~26-65 ?T). One research approach proposes that applying the electronic sum of two critical multiple resonance frequencies simultaneously may serve to more closely resemble real world biochemical changes as compared to applying these frequencies sequentially. Accordingly, it is suggested that applying the sum of the two individual resonance frequencies corresponding to H+ and H3O+ has the capacity to both increase proton density as well as couple to ATP synthase rotation. Not only will this tend to stabilize the F0 rotational rate but also perhaps make it feasible to control this rate, thereby providing a new and potentially efficacious means of treating diseases connected to mitochondrial dysfunction electromagnetically.

中文翻译:

Warburg 假说和弱 ELF 生物相互作用

摘要 Warburg 对癌细胞中 ATP 生成的观察分析了 H+ 共振效应对 ATP 合酶转子角速度的可能影响。可以合理地预期与线粒体功能障碍相关的各种疾病可能部分与 ATP 合酶的旋转速率有关。如文献中发现的,ATP 合酶旋转速率的实验测量结果与质子在洛伦兹力下移动的离子回旋共振 (ICR) 频率所预期的结果一致,洛伦兹力由地磁场的近似表面强度决定 (~26 -65 ?T)。一种研究方法提出,与顺序应用这些频率相比,同时应用两个关键多共振频率的电子总和可以更接近现实世界的生化变化。因此,建议应用对应于 H+ 和 H3O+ 的两个单独共振频率的总和具有增加质子密度以及与 ATP 合酶旋转耦合的能力。这不仅会趋于稳定 F0 旋转速率,而且可能使控制该速率成为可能,从而提供一种新的、潜在有效的方法来治疗与电磁线粒体功能障碍相关的疾病。建议应用对应于 H+ 和 H3O+ 的两个单独共振频率的总和具有增加质子密度以及与 ATP 合酶旋转耦合的能力。这不仅会趋于稳定 F0 旋转速率,而且可能使控制该速率成为可能,从而提供一种新的、潜在有效的方法来治疗与电磁线粒体功能障碍相关的疾病。建议应用对应于 H+ 和 H3O+ 的两个单独共振频率的总和具有增加质子密度以及与 ATP 合酶旋转耦合的能力。这不仅会趋于稳定 F0 旋转速率,而且可能使控制该速率成为可能,从而提供一种新的、潜在有效的方法来治疗与电磁线粒体功能障碍相关的疾病。
更新日期:2020-03-12
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