ABSTRACT

Objective: We tested the association of individual cognitive domains measured with the Mini-Mental State Examination (MMSE) and disability.

Method: Cross-sectional study in a population-based cohort aged ≥55 years (n = 4,803). Sample was divided into two groups: individuals with cognition within the normal range (CNR) (n = 4,057) and those with cognitive impairment (CI) (n = 746). Main outcome measures: The MMSE, the Katz Index (Basic Activities of Daily Living, bADL), the Lawton and Brody Scale (Instrumental Activities of Daily Living, iADL), and the Geriatric Mental State (GMS-AGECAT).

Results: MMSE-orientation was associated with disability in bADL, iADL and a decrease in social participation, regardless of cognitive status. MMSE-attention was associated with disability in iADL, but only in CNR. MMSE-language was associated with disability in bADL, iADL and with reduced social participation, but only in CI. Conclusions: The associations observed between disability and orientation may have clinical and public health implications.

摘要

目标：我们测试了个人认知领域与简易精神状态检查 (MMSE) 和残疾之间的关联。

方法：对年龄≥55 岁的人群队列进行横断面研究（n = 4,803）。样本分为两组：认知在正常范围内的个体 (CNR) (n = 4,057) 和认知障碍 (CI) 的个体 (n = 746)。主要结果测量：MMSE、Katz 指数（日常生活的基本活动，bADL）、Lawton 和 Brody 量表（日常生活的工具性活动，iADL）和老年精神状态 (GMS-AGECAT)。

结果： MMSE 取向与 bADL、iADL 的残疾和社会参与的减少有关，无论认知状态如何。MMSE 注意力与 iADL 中的残疾有关，但仅在 CNR 中。MMSE 语言与 bADL、iADL 的残疾和社会参与减少有关，但仅在 CI 中。结论：观察到的残疾和定向之间的关联可能具有临床和公共卫生影响。