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Clinically significant traumatic intracranial hemorrhage following minor head trauma in older adults: a retrospective cohort study.
Brain Injury ( IF 1.9 ) Pub Date : 2020-04-14 , DOI: 10.1080/02699052.2020.1753242
Toby O'Brien 1, 2 , Biswadev Mitra 2, 3 , Natalie Le Sage 1, 4 , Pier-Alexandre Tardif 1 , Marcel Emond 1, 4, 5 , Myreille D'Astous 6 , Eric Mercier 1, 4, 5
Affiliation  

OBJECTIVES The primary objective of this study was to determine the incidence of clinically significant traumatic intracranial hemorrhage (T-ICH) following minor head trauma in older adults. Secondary objective was to investigate the impact of anticoagulant and antiplatelet therapies on T-ICH incidence. METHODS This retrospective cohort study extracted data from electronic patient records. The cohort consisted of patients presenting after a fall and/or head injury and presented to one of five ED between 1st March 2010 and 31st July 2017. Inclusion criteria were age ≥ 65 years old and a minor head trauma defined as an impact to the head without fulfilling criteria for traumatic brain injury. RESULTS From the 1,000 electronic medical records evaluated, 311 cases were included. The mean age was 80.1 (SD 7.9) years. One hundred and eighty-nine (189) patients (60.8%) were on an anticoagulant (n = 69), antiplatelet (n = 130) or both (n = 16). Twenty patients (6.4%) developed a clinically significant T-ICH. Anticoagulation and/or antiplatelets therapies were not associated with an increased risk of clinically significant T-ICH in this cohort (Odds ratio (OR) 2.7, 95% CI 0.9-8.3). CONCLUSIONS In this cohort of older adults presenting to the ED following minor head trauma, the incidence of clinically significant T-ICH was 6.4%.

中文翻译:

老年人轻度头部外伤后临床上重大的颅内外伤性出血:一项回顾性队列研究。

目的本研究的主要目的是确定老年人轻度头部外伤后临床上具有重大临床意义的颅内出血(T-ICH)的发生率。次要目的是研究抗凝和抗血小板治疗对T-ICH发病率的影响。方法这项回顾性队列研究从电子病历中提取数据。该队列由在跌倒和/或头部受伤后出现并在2010年3月1日至2017年7月31日之间接受五次急诊就诊的患者组成。纳入标准为年龄≥65岁,头部轻微外伤定义为对头部的影响没有达到颅脑外伤的标准。结果从评估的1,000份电子病历中,包括311例。平均年龄为80.1(SD 7.9)岁。一百八十九(189)例患者(60.8%)接受抗凝剂(n = 69),抗血小板(n = 130)或两者(n = 16)。20名患者(6.4%)出现了具有临床意义的T-ICH。在该队列中,抗凝和/或抗血小板治疗与临床上显着的T-ICH风险增加无关(几率(OR)2.7,95%CI 0.9-8.3)。结论在这个队列中,在头部轻微外伤后出现急诊室的老年人中,具有临床意义的T-ICH发生率为6.4%。
更新日期:2020-04-14
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