Abstract The symbiotic association of the leaf-cutter ants with the fungus Leucoagaricus gongylophorus implies that the negative impact on the fungi will affect the survival of the ants. After a promising antifungal bioactivity, Carica papaya was studied leading to the bioassay-guided isolation of squalene, 4,5-dihydrohumulen, the flavanol-glycosides quercetin, kaempferol, and rutin, and the alkaloid carpaine. Carpaine and squalene were found to have a moderate individual activity, which increased when evaluated together. Based on the presence of these compounds, standardized extracts were formulated for field tests on nests of Acromyrmex octospinosus. All the nests treated were negatively affected evidencing a promising lead for the integrated management of leaf-cutter ants.

中文翻译：

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用番木瓜抑制 Leucoagaricus gongylophorus：控制切叶蚁 Acromyrmex octospinosus 的替代方法

摘要 切叶蚁与真菌Leucoagaricus gongylophorus 的共生关系意味着对真菌的负面影响将影响蚂蚁的生存。在获得有希望的抗真菌生物活性后，木瓜被研究导致角鲨烯、4,5-二氢葎草烯、黄烷醇糖苷槲皮素、山奈酚和芦丁以及生物碱卡巴因的生物测定指导分离。发现 Carpaine 和角鲨烯具有中等的个体活性，当一起评估时会增加。基于这些化合物的存在，标准化提取物被配制用于对 Acromyrmex octospinosus 巢进行实地测试。所有处理过的巢都受到负面影响，这证明了对切叶蚁进行综合管理的有希望的领导。