Supercritical fluids offer considerable advantages for the isolation of natural products. Supercritical fluids can be used as antisolvents to precipitate selectively target compounds from a mixture and to remove impurities by the Supercritical Antisolvent technique (SAS). The present decade has experienced a considerable increase in the number of publications that apply this technique to natural extracts, especially for the isolation of polyphenols and carotenoids from plants and microalgae. However, the lack of a clear terminology and purpose adds confusion to the topic. The proposed review aims at defining a research field that consists in applying SAS to natural extracts for the purification of target compounds. To do so, we trace back the origin of the field, discuss the different terminology used to refer to such processes, and suggest appropriate terms for the process and for reported results. This work explores the scope of the topic by compiling all works published to date from a scattered literature, using all possible process terminologies for the search. The information given aims to highlight the most promising applications explored so far and possibly inspire further research.

超临界流体为分离天然产物提供了相当大的优势。超临界流体可用作抗溶剂，以从混合物中选择性沉淀出目标化合物，并通过超临界抗溶剂技术（SAS）去除杂质。目前的十年中，将这种技术应用于天然提取物的出版物数量已大大增加，特别是从植物和微藻中分离多酚和类胡萝卜素的出版物。但是，缺乏明确的术语和目的使该主题更加混乱。拟议的审查旨在定义一个研究领域，该领域包括将SAS应用于天然提取物以纯化目标化合物。为此，我们追溯该领域的起源，讨论用于指代此类过程的不同术语，并为该过程和报告的结果提出适当的术语。这项工作使用所有可能的搜索过程术语，通过汇总零星文献中迄今为止出版的所有著作来探索主题的范围。所提供的信息旨在突出显示迄今为止探索的最有希望的应用程序，并可能激发进一步的研究。