As their illness progresses, patients with Multiple Sclerosis (MS) may suffer from motor impairments. In the present study, we examined the effectiveness of three interventions for learning a bimanual coordination task: Virtual reality training (VRT), conventional physical training (CPT), and the combination of VRT and CPT (COMB). A total of 45 women with MS were randomly assigned to one of the following study conditions: VRT, CPT or COMB. Bimanual coordination was assessed at baseline, eight weeks later at study completion, and 4 weeks after that at follow-up. Bimanual coordination improved over time from baseline to study completion and to follow-up. Compared to the VRT and CPT conditions, the COMB condition led to higher coordination accuracy and consistency. The combination thus appears to have the potential to speed up the recovery of motor control and rehabilitation of women with MS.

中文翻译：

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虚拟现实和体育训练相结合改善了多发性硬化症女性的双手协调能力

随着病情的发展，多发性硬化症 (MS) 患者可能会出现运动障碍。在本研究中，我们检查了学习双手协调任务的三种干预措施的有效性：虚拟现实训练 (VRT)、传统体育训练 (CPT) 以及 VRT 和 CPT 的组合 (COMB)。总共 45 名 MS 女性被随机分配到以下研究条件之一：VRT、CPT 或 COMB。在基线、8 周后研究完成时和 4 周后随访时评估双手协调。从基线到研究完成再到随访，双手协调随着时间的推移而得到改善。与 VRT 和 CPT 条件相比，COMB 条件导致更高的协调精度和一致性。