Abstract

Objective

To analyze an association of eating disorders (EDs) to reproductive health outcomes among former adolescent psychiatric inpatients, hospitalized between the ages 13 and 17 years. The register-based follow-up information on psychiatric comorbidity and use of prescribed addictive psychotropic medication up to early adulthood were also explored.

Methods

A total of 31 (10.3%) women with a diagnosed ED were identified from the initial sample of 300 female adolescents, treated in psychiatric inpatient care between 2001 and 2006. The K-SADS-PL and EuropASI research instruments were used to gather information during the adolescent psychiatric hospitalization. The follow-up data for reproductive health outcomes and psychiatric comorbidity up to early adulthood were obtained from the national health care registers. Information on prescribed addictive psychotropic medication was provided by the Social Insurance Institution of Finland. In analyses, EDs were categorized into anorexia nervosa (AN) and other EDs (OED). AN accounted for 58.1% of all EDs. Of OEDs, the majority (69.1%) were bulimia.

Results

None of the women with AN, but 53.8% of those with OED had undergone medical abortions by early adulthood. Childbirths were emphasized in women with OED (61.5%) and a history of hospital-treated poisonings in women with AN (55.6%). High nicotine dependence in adolescence (30.8%) was a characteristic of women with OED.

Conclusion

Our study findings suggest that OED may expose affected women to various unfavorable reproductive health outcomes, particularly women with a history of psychiatric admissions. Recognizing the differences in young women with different subtypes of ED is important when discussing contraception and pregnancy.

中文翻译：

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饮食失调女性的生殖健康结果：前青春期精神病住院患者的基于登记的随访研究

摘要

客观的

分析 13 至 17 岁住院的前青少年精神病住院患者的饮食失调 (ED) 与生殖健康结果的关联。还探讨了基于登记册的有关精神疾病和使用处方成瘾精神药物直至成年早期的随访信息。

方法

从 2001 年至 2006 年间在精神病住院治疗中接受治疗的 300 名女性青少年的初始样本中确定了总共 31 名（10.3%）被诊断为 ED 的女性。K-SADS-PL 和 EuropASI 研究工具用于在青少年精神科住院。直到成年早期的生殖健康结果和精神疾病的随访数据来自国家卫生保健登记册。芬兰社会保险机构提供了有关处方成瘾性精神药物的信息。在分析中，EDs 分为神经性厌食症 (AN) 和其他 EDs (OED)。AN 占所有 ED 的 58.1%。在 OED 中，大多数 (69.1%) 是贪食症。

结果

没有 AN 女性，但 53.8% 的 OED 女性在成年早期进行过药物流产。OED 女性（61.5%）强调分娩，AN 女性有住院治疗中毒史（55.6%）。青春期尼古丁高度依赖（30.8%）是 OED 女性的一个特征。

结论

我们的研究结果表明，OED 可能会使受影响的女性面临各种不利的生殖健康结果，尤其是有精神病入院史的女性。在讨论避孕和怀孕时，认识到不同亚型 ED 的年轻女性的差异很重要。