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Phytochemical profiling, antioxidant and antimicrobial effectiveness of Rosmarinus tournefortii De Noe extracts issued from different regions of Algeria
Journal of Essential Oil Research ( IF 2.2 ) Pub Date : 2020-03-30 , DOI: 10.1080/10412905.2020.1737587
Tidya Outaleb 1 , Amine Yekkour 2, 3 , Mohamed Hazzit 1 , Abdelghani Zitouni 3 , Nasseredine Sabaou 3
Affiliation  

ABSTRACT Rosmarinus tournefortii is an aromatic evergreen shrub endemic to North Africa, including Algeria. Reports on phytochemicals of this species and related biological activities remain scarce. The essential oils (EOs) and ethanol extracts (EEs) of five populations collected in Algeria are investigated for their antioxidant and antimicrobial properties through different multivariate statistical methods. EOs analysis by GC and GC-MS showed that the main constituents (α-pinene, camphor, camphene and limonene) were almost comparable. The antioxidant capacity was evaluated by the ferric reducing power and the inhibition of free radicals DPPH● and ABTS●+. The free radical scavenging effectiveness of EEs was about 2 times higher than the standard antioxidant (BHT). EOs exhibited weaker antioxidant activity insofar they failed to scavenge 50% radicals. The antimicrobial activity evaluated by determining the minimum inhibitory/bactericidal concentrations towards fifteen multi-drug resistant microorganisms showed that EEs were the most active. The Gram-positive bacteria were the most susceptible. Both EEs and EOs exhibited antifungal and anti-yeast activities.

中文翻译:

来自阿尔及利亚不同地区的 Rosmarinus tournefortii De Noe 提取物的植物化学分析、抗氧化和抗菌效果

摘要 Rosmarinus tournefortii 是一种芳香的常绿灌木,原产于北非,包括阿尔及利亚。关于该物种的植物化学物质和相关生物活动的报告仍然很少。通过不同的多元统计方法研究了在阿尔及利亚收集的五个种群的精油 (EOs) 和乙醇提取物 (EEs) 的抗氧化和抗菌特性。GC 和 GC-MS 的 EO 分析表明,主要成分(α-蒎烯、樟脑、莰烯和柠檬烯)几乎具有可比性。抗氧化能力通过三价铁还原能力和对自由基DPPH●和ABTS●+的抑制来评价。EEs 的自由基清除效果比标准抗氧化剂 (BHT) 高约 2 倍。EOs 表现出较弱的抗氧化活性,因为它们无法清除 50% 的自由基。通过确定对 15 种多重耐药微生物的最小抑制/杀菌浓度评估的抗菌活性表明,EEs 是最活跃的。革兰氏阳性菌是最敏感的。EE 和 EO 均表现出抗真菌和抗酵母活性。
更新日期:2020-03-30
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