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Dedicated 70 MHz RF systems for hyperthermia of challenging tumor locations
International Journal of Microwave and Wireless Technologies ( IF 1.4 ) Pub Date : 2020-04-13 , DOI: 10.1017/s1759078720000318
Johannes Crezee , Remko Zweije , Jan Sijbrands , H. Petra Kok

Hyperthermia (i.e. heating of tumor tissue to 40–43°C) is used in clinical oncology to enhance the therapeutic effect of chemotherapy and radiotherapy. Many tumor sites are heated either by a single RF or MW antenna positioned on the tumor location, or by a phased array positioned around the patient. Superficial tumors are generally heated with MW antennas (434–2450 MHz) and deep-seated tumors with RF antennas (70–150 MHz). These devices cover the major, more common tumor sites, but more rare locations require more dedicated applicators. We discuss dedicated RF systems aiming for heating semi-deep-seated tumors in the leg, breast, and upper thorax. Clinical results show that adequate heating is possible with these systems, with achieved temperatures in the therapeutic range.

中文翻译:

专用的 70 MHz 射频系统,用于对具有挑战性的肿瘤位置进行热疗

热疗(即将肿瘤组织加热到 40–43°C)用于临床肿瘤学以增强化学疗法和放射疗法的治疗效果。许多肿瘤部位要么通过位于肿瘤位置的单个 RF 或 MW 天线进行加热,要么通过位于患者周围的相控阵进行加热。浅表肿瘤通常用 MW 天线 (434-2450 MHz) 加热,深部肿瘤用 RF 天线 (70-150 MHz) 加热。这些设备覆盖了主要、更常见的肿瘤部位,但更罕见的部位需要更多专用的施药器。我们讨论了用于加热腿部、乳房和上胸部的半深部肿瘤的专用射频系统。临床结果表明,这些系统可以充分加热,达到治疗范围内的温度。
更新日期:2020-04-13
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