SummaryTumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) are cytokines that are involved in the development, proliferation and apoptosis of ovarian follicular cells in domestic mammals. The expression of these cytokines in various follicular compartments, depending on the stage of follicle development, demonstrates their involvement in the control of primordial follicle growth up to the preovulatory stage. The mechanism of action of these factors depends on the presence of their receptors that transduce their biological actions. This review shows the expression sites of TNF-α, IL-1β and their receptors in ovarian follicles, and discusses the mechanism of action of these cytokines during follicle development, oocyte maturation and ovulation in domestic animals.

中文翻译：

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卵巢卵泡中的白细胞介素 1β 和 TNF-α 系统及其在卵泡发育、卵母细胞成熟和排卵过程中的作用

摘要肿瘤坏死因子-α（TNF-α）和白细胞介素-1β（IL-1β）是参与家养哺乳动物卵巢滤泡细胞发育、增殖和凋亡的细胞因子。这些细胞因子在不同卵泡区室中的表达，取决于卵泡发育的阶段，表明它们参与控制原始卵泡生长直至排卵前阶段。这些因子的作用机制取决于它们的受体的存在，这些受体可以转导它们的生物作用。本文综述了TNF-α、IL-1β及其受体在卵泡中的表达位点，并讨论了这些细胞因子在家畜卵泡发育、卵母细胞成熟和排卵过程中的作用机制。