SummaryInfertility is the most common issue in the field of reproductive medicine. Many factors affect fertility status, including life-style choices such as cigarette smoking or alcohol use. The aim of this study was to investigate the effects of cigarette smoking on oocyte quality as well the quantity in young fertile women. In total, 56 young fertile women who were undergoing oocyte donation programmes were included in this study. The effects of cigarette smoking on antral follicle count, number of follicles and oocytes retrieved and morphology were assessed by an expert embryologist. The results of this study showed that cigarette smoking did not have a significant effect on the follicle count or the number of oocytes retrieved from young and fertile women. However, a significant difference was observed in the morphological assessment. In conclusion, although cigarette smoking does not seem to affect oocyte development, it had an effect on cytoplasmic anomalies and therefore may lower pregnancy chance. Therefore, it is crucial to give proper counselling to patients who are trying to become pregnant both naturally and by in vitro fertilization.

中文翻译：

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吸烟真的对卵泡发生和卵母细胞成熟有临床影响吗？

摘要不孕不育是生殖医学领域最常见的问题。许多因素会影响生育状况，包括生活方式选择，例如吸烟或饮酒。本研究的目的是调查吸烟对年轻可育女性卵母细胞质量和数量的影响。本研究共纳入了 56 名正在接受卵母细胞捐赠计划的年轻有生育能力的女性。专家胚胎学家评估了吸烟对窦卵泡计数、卵泡和卵母细胞数量以及形态的影响。这项研究的结果表明，吸烟对卵泡计数或从年轻和有生育能力的女性中提取的卵母细胞数量没有显着影响。然而，在形态学评估中观察到显着差异。总之，虽然吸烟似乎不会影响卵母细胞的发育，但它对细胞质异常有影响，因此可能会降低怀孕机会。因此，为尝试自然怀孕和通过怀孕的患者提供适当的咨询至关重要。体外施肥。