Abstract A sensitive and selective molecular-imprinted electrochemical sensor was developed for the determination of ampicillin. The molecularly imprinted film was electropolymerized on the surface of a glassy carbon electrode modified with gold nanoparticles (AuNPs) and single walled carbon nanotubes (SWCNTs) using ampicillin as the template molecule and o-phenylendiamine as the functional monomer. Under the optimized conditions, the current change of this electrode showed a linear relationship with the ampicillin concentration from 5.0 × 10−8 mol/L to 1.0 × 10−5 mol/L and a detection limit of 1.0 × 10−9 mol/L. Due to the increased specific surface areas and conductivity of the AuNPs and SWCNTs, this sensor exhibited excellent sensitivity for ampicillin. The recovery values for ampicillin detection in milk using the developed sensor were from 95.0% to 98.1%.

中文翻译：

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基于电聚合聚（邻苯二胺）/金纳米粒子/单壁碳纳米管修饰玻碳电极电化学测定氨苄青霉素

摘要 研制了一种灵敏、选择性强的分子印迹电化学传感器，用于氨苄青霉素的测定。使用氨苄青霉素作为模板分子和邻苯二胺作为功能单体，在用金纳米粒子 (AuNPs) 和单壁碳纳米管 (SWCNTs) 修饰的玻碳电极表面上电聚合分子印迹膜。在优化条件下，该电极的电流变化与氨苄青霉素浓度从5.0×10-8 mol/L到1.0×10-5 mol/L呈线性关系，检出限为1.0×10-9 mol/L . 由于 AuNPs 和 SWCNTs 的比表面积和电导率增加，该传感器对氨苄青霉素表现出优异的灵敏度。使用开发的传感器检测牛奶中氨苄青霉素的回收率为 95。