The Charcot‐Marie‐Tooth disease Pediatric Scale (CMTPedS) is a Rasch‐built clinical outcome measure of disease severity. It is valid, reliable, and responsive to change for children and adolescents aged 3 to 20 years. The aim of this study was to translate and validate an Italian version of the CMTPedS using a validated framework of transcultural adaptation. The CMTPedS (Italian) was translated and culturally adapted from source into Italian by two experts in CMT with good English language proficiency. The two translations were reviewed by a panel of experts in CMT. The agreed provisional version was back translated into English by a professional translator. The definitive Italian version was developed during a consensus teleconference by the same panel. CMT patients were assessed with the final version of the outcome measure and a subset had a second assessment after 2 weeks to evaluate test‐retest reliability. Seventeen patients with CMT aged 5 to 20 years (eight female) were evaluated with the CMTPedS (Italian), and test‐retest was performed in three patients. The CMTPedS (Italian) showed a high test‐retest reliability. No patient had difficulty in completing the scale. The instructions for the different items were clearly understood by clinicians and therefore the administration of the outcome measure was straight forward and easily understood by the children assessed. The CMTPedS (Italian) will be used for clinical follow‐up and in clinical research studies in the Italian population. The data is fully comparable to that obtained from the English language version.

中文翻译：

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夏科特-玛丽牙齿疾病儿科量表的意大利语版本的验证。

Charcot‐Marie‐Tooth疾病儿科量表（CMTPedS）是Rasch建立的疾病严重程度的临床预后指标。它对3到20岁的儿童和青少年有效，可靠并能应对变化。这项研究的目的是使用经过验证的跨文化适应框架来翻译和验证意大利语版本的CMTPedS。CMTPedS（意大利语）是由两名具有良好英语水平的CMT专家从意大利语翻译并从文化上改编成意大利语的。CMT专家小组审查了这两种翻译。由专业翻译人员将商定的暂定版本翻译回英语。最终的意大利语版本是在同一小组的共识电话会议期间开发的。对CMT患者进行了最终评估，并在2周后对一部分患者进行了第二次评估，以评估重测信度。使用CMTPedS（意大利语）评估了17例5至20岁的CMT患者（八名女性），并对三名患者进行了重新测试。CMTPedS（意大利语）显示出很高的重试可靠性。没有患者在完成量表时有困难。临床医生清楚地理解了有关不同项目的说明，因此，对结果进行评估的方法很简单，被评估的儿童也容易理解。CMTPedS（意大利语）将用于意大利人群的临床随访和临床研究。数据与从英语版本获得的数据完全可比。