Abstract There are contrary reports in the application of low protein diet (LPD) in laying hens. The present study was conducted to explore the effects of LPD on the laying performance, hepatic lipogenesis, and expression of appetite-associated genes in laying hens. A total of 240 laying hens were randomly divided into two groups: one was fed diet contains 9.2 % crude protein (LPD) and the other received 16.5 % protein (Control). LPD decreased (P 0.05) on peroxisome proliferator-activated receptors α (PPAR-α), and sterol regulatory element binding proteins 1c (SREBP-1c). In contrast to the changed mRNA levels, the hepatic activities of FAS and malic enzyme (ME) were not influenced (P > 0.05) by LPD treatment. Adversely, the expression of apolipoprotein B (ApoB), apolipoprotein very-low density lipoportein (ApoVLDL) and carnitine palmitoyl transferase 1 (CPT1) were downregulated (P

中文翻译：

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补充结晶氨基酸的低蛋白日粮抑制蛋鸡的食欲和载脂蛋白合成

摘要 低蛋白日粮（LPD）在蛋鸡中的应用有相反的报道。本研究旨在探讨 LPD 对蛋鸡产蛋性能、肝脏脂肪生成和食欲相关基因表达的影响。总共 240 只蛋鸡被随机分为两组：一组饲喂含有 9.2% 粗蛋白 (LPD) 的日粮，另一组饲喂 16.5% 的蛋白质（对照）。过氧化物酶体增殖物激活受体 α (PPAR-α) 和甾醇调节元件结合蛋白 1c (SREBP-1c) 的 LPD 降低 (P = 0.05)。与改变的 mRNA 水平相反，LPD 处理不影响 FAS 和苹果酸酶 (ME) 的肝脏活性（P > 0.05）。反之，载脂蛋白 B (ApoB) 的表达，