BACKGROUND Syringe services programs (SSPs) are an evidence-based harm reduction strategy that reduces dangerous sequelae of injection drug use among people who inject drugs (PWID) such as overdose. SSP services include safer injection education and community-based naloxone distribution programs. This study evaluates differences in overdose-associated hospital admissions following the implementation of the first legal SSP in Florida, based in Miami-Dade County. METHODS We performed a retrospective analysis of hospitalizations for injection drug-related sequelae at a county hospital before and after the implementation of the SSP. An algorithm utilizing ICD-10 codes for opioid use and sequelae was used to identify people who inject opioids (PWIO). Florida Department of Law Enforcement Medical Examiners Commission Report data was used to analyze concurrent overdose death trends in Florida counties. RESULTS Over the 25-month study period, 302 PWIO admissions were identified: 146 in the pre-index period vs. 156 in the post-index period. A total of 26 admissions with PWIO overdose were found: 20 pre-index and 6 post-index (p = 0.0034). CONCLUSIONS Declining overdose-associated admissions among PWIO suggests early impacts following SSP implementation. These results indicate a potential early benefit of SSP that should be further explored for its effects on future hospital admission and mortality.

中文翻译：

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在实施注射器服务计划后注射阿片类药物的人中的住院人数。

背景技术注射器服务程序（SSP）是一种基于证据的伤害减轻策略，可减少在注射药物（PWID）的人中服用过量药物等危险的后遗症。SSP服务包括更安全的注射教育和基于社区的纳洛酮分发计划。这项研究评估了迈阿密-戴德县基于佛罗里达州的第一个合法的SSP实施后与药物过量相关的住院人数的差异。方法我们对SSP实施前后在县级医院注射药物相关后遗症的住院治疗进行了回顾性分析。一种使用ICD-10代码进行阿片类药物使用和后遗症的算法被用来识别注射阿片类药物的人（PWIO）。佛罗里达州执法部医学检查员委员会的报告数据用于分析佛罗里达州各县并发的过量死亡趋势。结果在为期25个月的研究期内，确定了302例PWIO入院：索引前期为146个，索引后期为156个。发现总共有26例PWIO过量入院：指数前20次和指数后6次（p = 0.0034）。结论PWIO中与药物过量相关的入院人数下降表明SSP实施后的早期影响。这些结果表明，SSP可能具有早期获益，应进一步探讨其对未来住院和死亡率的影响。发现总共有26例PWIO过量入院：指数前20次和指数后6次（p = 0.0034）。结论PWIO中与药物过量相关的入院人数下降表明SSP实施后的早期影响。这些结果表明，SSP可能具有早期获益，应进一步探讨其对未来住院和死亡率的影响。总共发现26例PWIO过量的入院患者：指数前20例和指数后6例（p = 0.0034）。结论PWIO中与药物过量相关的入院人数下降表明SSP实施后的早期影响。这些结果表明，SSP可能具有早期获益，应进一步探讨其对未来住院和死亡率的影响。