A proportion of people who have been diagnosed with peripheral arterial disease and diabetes mellitus will be susceptible to chronic wounds. Oxygen is vital for wound healing, so oxygen measurements should to be taken as predictive values for wound healing in patients. When measuring oxygen at the wound bed, there is potentially a risk of cross-infection if no protective barrier is used; and skin stripping if an adhesive barrier is used on the wound bed. This cross sectional within subject repeated measures pilot study, aims to determine if the application of opsite film, as an infection control measure, in one or two layers, impacts on tissue oxygenation readings obtained when using the MoorVMS-OXY. Mean oxygen saturation percentages were measured from 29 limbs of 18 healthy participants. Oxygen saturation was measured for 20 s and analysed at the first metatarsophalangeal joint using no film, one and two layers using the MoorVMS-OXY. A one-way repeated ANOVA with a Bonferroni post hoc test was performed to test for statistically significant differences between the values of the three parameters and multiple pairwise comparisons was completed. Amongst the three layers, there was a statistically significant difference in oxygen saturation between the two layers of Opsite Flexigrid and none; and also between the two layers of Flexigrid and single layer (p < 0.05). It was also established that there was no statistically significant difference between the single layer of Opsite Flexigrid and no Flexigrid layer (p > 0.05). The results imply that one layer of Opsite Flexigrid is a suitable protective barrier to use when establishing capillary bed oxygen perfusion with the MoorVMS-OXY. However, the application of two Opsite Flexigrid layers, to prevent skin stripping, decreases the recorded values of oxygen saturation percentages significantly, therefore providing inaccurate results. Indicating that a double layer cannot be used over ulceration sites if measuring oxygen levels at the wound bed.

中文翻译：

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Opsite⋄ Flexigrid⋄ 的应用是否会遮挡使用 moorVMS-OXY 机器的健康个体的氧饱和度读数？

一部分被诊断出患有外周动脉疾病和糖尿病的人容易受到慢性伤口的影响。氧气对于伤口愈合至关重要，因此应将氧气测量值作为患者伤口愈合的预测值。在伤口床测量氧气时，如果不使用保护屏障，可能存在交叉感染的风险；如果在伤口床上使用粘性屏障，则皮肤剥离。受试者重复测量试验研究中的这一横截面旨在确定在一层或两层中应用异位膜作为感染控制措施是否会影响使用 MoorVMS-OXY 时获得的组织氧合读数。测量了 18 名健康参与者的 29 条肢体的平均氧饱和度百分比。测量氧饱和度 20 秒，并使用 MoorVMS-OXY 在第一跖趾关节处分析，不使用薄膜，一层和两层。执行具有 Bonferroni 事后检验的单向重复方差分析，以检验三个参数值之间的统计学显着差异，并完成多个成对比较。在三层中，Opsite Flexigrid 两层之间的氧饱和度在统计学上有显着差异，没有；以及两层 Flexigrid 和单层之间（p < 0.05）。还确定单层 Opsite Flexigrid 和无 Flexigrid 层之间没有统计学显着差异（p > 0.05）。结果表明，当使用 MoorVMS-OXY 建立毛细管床氧气灌注时，一层 Opsite Flexigrid 是合适的保护屏障。然而，应用两个 Opsite Flexigrid 层以防止皮肤剥离，显着降低了氧饱和度百分比的记录值，因此提供了不准确的结果。如果测量伤口床的氧气水平，表明不能在溃疡部位使用双层。