Circuit topology is emerging as a versatile measure to classify the internal structures of folded linear polymers such as proteins and nucleic acids. The topology framework can be applied to a wide range of problems, most notably molecular folding reactions that are central to biology and molecular engineering. In this Outlook, we discuss the state-of-the art of the technology and elaborate on the opportunities and challenges that lie ahead.

中文翻译：

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聚合物折叠反应的电路拓扑分析。

电路拓扑作为一种通用的方法正在出现，可以对折叠的线性聚合物（例如蛋白质和核酸）的内部结构进行分类。拓扑框架可以应用于各种各样的问题，尤其是对于生物学和分子工程至关重要的分子折叠反应。在本《展望》中，我们讨论了该技术的最新发展，并详细阐述了未来的机遇和挑战。