Rational lifestyle engineering using computational methods and synthetic biology has made it possible to genetically improve industrial performance of microbial cell factories for the production of a range of biobased chemicals. However, only an estimated 1 in 5,000 to 10,000 innovations make it through the Valley of Death to market implementation.

中文翻译：

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穿越死亡之谷：工业界和学术界对生产平台和机会的看法

使用计算方法和合成生物学进行合理的生活方式工程，使得从基因上改善微生物细胞工厂的工业性能，以生产一系列生物基化学品成为可能。但是，估计只有5,000到10,000个创新中的1个能够通过死亡之谷进入市场。