Background Angiotensin-converting enzyme-2 (ACE2) overexpression improves left ventricular remodeling and function in diabetic cardiomyopathy; however, the effect of ACE2-overexpressed mesenchymal stem cells (MSCs) on myocardial infarction (MI) remains unexplored. This study aimed to investigate the effect of ACE2-overexpression on the function of MSCs and the therapeutic efficacy of MSCs for MI.

中文翻译：

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过度表达血管紧张素转换酶2的间充质干细胞改善了心肌梗死大鼠模型的微环境和心脏功能

背景血管紧张素转换酶2（ACE2）的过表达改善了糖尿病性心肌病的左心室重构和功能。然而，ACE2过度表达的间充质干细胞（MSCs）对心肌梗死（MI）的影响仍待探索。本研究旨在探讨ACE2过表达对MSCs功能的影响以及MSCs对MI的治疗作用。