Sepsis is a life-threatening condition due to a dysregulated immunological response to infection. Apart from source control and broad-spectrum antibiotics, management is based on fluid resuscitation and vasoactive drugs. Fluid resuscitation implicates the risk of volume overload, which in turn is associated with longer stay in intensive care, prolonged use of mechanical ventilation and increased mortality.

中文翻译：

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抗分泌肽AF-16在实验性腹膜炎诱发的败血症中是否能调节体液平衡和炎症？

由于对感染的免疫反应失调，败血症是危及生命的疾病。除源控制和广谱抗生素外，治疗还基于液体复苏和血管活性药物。进行液体复苏有可能导致容量超负荷，这又与重症监护病房停留时间较长，机械通气时间延长以及死亡率增加有关。