Background. The prevalence of symptomatic COVID-19 in children remains low to date. In just a few months, COVID-19 has affected millions of people worldwide, and as of the date of this publication, the pandemic continues. Based on the current available evidence, children do not appear to be at higher risk of contracting COVID-19 than adults. However, children with neurological and neuromuscular conditions are vulnerable to the respiratory complications of other viral infections. Objectives. To assess whether children with brain-based developmental disabilities were more likely to develop COVID-19 and have complications or poorer outcomes following infection. Methods. We conducted a two-week rapid review on studies with primary data regarding children aged between zero and 18 years old with brain-based developmental disabilities, or who were at risk of developing such disabilities, with confirmed or suspected COVID-19. We performed our literature searches on April 18, 2020. Results. Our search strategy identified 538 individual records, of which four were included in our review. Of the 50 COVID-19 pediatric patients reported in the included studies, a total of seven children were at risk of developing brain-based disabilities. Symptoms ranged in severity. However, generally, patients were discharged or saw improvements in their symptoms by the end of the study period. No deaths were reported. Discussion. Our study highlights a knowledge gap regarding the impact of COVID-19 in children with brain-based developmental disabilities.

中文翻译：

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脑源性发育障碍儿童的COVID-19：快速回顾

背景。迄今为止，儿童症状性COVID-19的患病率仍然很低。在短短几个月内，COVID-19已影响全球数百万人，并且自本出版物发行之日起，大流行仍在继续。根据目前可获得的证据，儿童患COVID-19的风险似乎没有成年人高。但是，患有神经系统疾病和神经肌肉疾病的儿童容易受到其他病毒感染的呼吸系统并发症的影响。目标。评估患有脑源性发育障碍的儿童感染后是否更有可能发展COVID-19并发并发症或较差的预后。方法。我们对研究进行了为期两周的快速审查，研究的主要数据是0至18岁的脑性发育障碍儿童，或有确诊或疑似COVID-19的患上此类残疾风险的人。我们于2020年4月18日进行了文献检索。结果。我们的搜索策略确定了538条个人记录，其中有4条记录包含在我们的评论中。在纳入研究中报告的50名COVID-19儿科患者中，共有7名儿童有发展为基于脑的残疾的风险。症状轻重不等。但是，一般而言，到研究期结束时，患者已出院或症状有所改善。没有死亡的报道。讨论。我们的研究突出了关于COVID-19对脑源性发育障碍儿童的影响的知识差距。我们的搜索策略确定了538条个人记录，其中有4条记录包含在我们的评论中。在纳入的研究中报告的50名COVID-19儿科患者中，共有7名儿童有发展为基于脑的残疾的风险。症状轻重不等。但是，一般而言，到研究期结束时，患者已出院或症状有所改善。没有死亡的报道。讨论。我们的研究突出了关于COVID-19对脑源性发育障碍儿童的影响的知识差距。我们的搜索策略确定了538条个人记录，其中有4条记录包含在我们的评论中。在纳入的研究中报告的50名COVID-19儿科患者中，共有7名儿童有发展为基于脑的残疾的风险。症状轻重不等。但是，一般而言，到研究期结束时，患者已出院或症状有所改善。没有死亡的报道。讨论。我们的研究突出了关于COVID-19对脑源性发育障碍儿童的影响的知识差距。在研究期结束时，患者已出院或症状有所改善。没有死亡的报道。讨论。我们的研究突出了关于COVID-19对脑源性发育障碍儿童的影响的知识差距。在研究期结束时，患者已出院或症状有所改善。没有死亡的报道。讨论。我们的研究突出了关于COVID-19对脑源性发育障碍儿童的影响的知识差距。