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Differential Effects of Pathological Beta Burst Dynamics Between Parkinson’s Disease Phenotypes Across Different Movements
medRxiv - Neurology Pub Date : 2021-08-14 , DOI: 10.1101/2020.04.12.20063032
Raumin S Neuville , Ross W Anderson , Matthew N Petrucci , Jordan E Parker , Kevin B Wilkins , Anca Velisar , Helen M Bronte-Stewart

Background Resting state beta band (13 – 30 Hz) oscillations represent pathological neural activity in Parkinson’s disease (PD). It is unknown how the peak frequency or dynamics of beta oscillations may change among fine, limb and axial movements and different disease phenotypes. This will be critical for the development of personalized closed loop deep brain stimulation (DBS) algorithms during different activity states.

中文翻译:

不同运动中帕金森病表型间病理性 Beta 爆发动力学的差异效应

背景静息状态 β 波段 (13 – 30 Hz) 振荡代表帕金森病 (PD) 中的病理性神经活动。目前尚不清楚 β 振荡的峰值频率或动力学如何在精细、肢体和轴向运动以及不同疾病表型之间发生变化。这对于在不同活动状态下开发个性化闭环深部脑刺激 (DBS) 算法至关重要。
更新日期:2021-08-16
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