Susceptibility to infection such as SARS-CoV-2 may be influenced by host genotype. TwinsUK volunteers (n=2633) completing the C-19 Covid symptom tracker app allowed classical twin studies of covid-19 symptoms including predicted covid-19, a symptom-based algorithm predicting true infection derived in app users tested for SARS-CoV-2. We found heritability for fever = 41 (95% confidence intervals 12-70)%; anosmia 47 (27-67)%; delirium 49 (24-75)%; and predicted covid-19 gave heritability = 50 (29-70)%.

中文翻译：

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covid-19的自我报告症状（包括最能预测SARS-CoV-2感染的症状）是可遗传的

感染的易感性（例如SARS-CoV-2）可能会受到宿主基因型的影响。TwinsUK志愿者（n = 2633）完成了C-19 Covid症状追踪器应用程序后，就可以对covid-19症状进行经典的双胞胎研究，包括预测的covid-19，这是一种基于症状的算法，可预测通过SARS-CoV-2测试的应用程序用户获得的真实感染。我们发现发烧的遗传力= 41（95％置信区间12-70）％；失眠症47（27-67）％; ir 49（24-75）％; 预测的covid-19的遗传力= 50（29-70）％。