FastLORS is a software package that implements a new algorithm to solve sparse multivariate regression for expression quantitative trait loci (eQTLs) mapping. FastLORS solves the same optimization problem as LORS, an existing popular algorithm. The optimization problem is solved through inexact block coordinate descent with updates by proximal gradient steps, which reduces the computational cost compared with LORS. We apply LORS and FastLORS to a real dataset for eQTL mapping and demonstrate that FastLORS delivers comparable results with LORS in much less computing time.

中文翻译：

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FastLORS：R中表达定量性状基因座定位的联合建模

FastLORS是一个软件包，该软件包实施一种新算法来解决稀疏多元回归以进行表达定量性状基因座（eQTL）映射的问题。FastLORS解决了与现有流行算法LORS相同的优化问题。通过不精确的块坐标下降来解决优化问题，并通过近端梯度步长进行更新，与LORS相比，降低了计算成本。我们将LORS和FastLORS应用于真实的数据集以进行eQTL映射，并证明FastLORS可在更少的计算时间内提供与LORS相当的结果。