Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.,Journal of Pharmacy and Pharmacology

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Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.
Journal of Pharmacy and Pharmacology ( IF 2.8 ) Pub Date : 2020-05-11 , DOI: 10.1111/jphp.13280
Jiang Xu ₁ , Ping Xiang ₂ , Linqing Liu ₃ , Jianran Sun ₁ , Shandong Ye ₁

Affiliation

Metformin (MET) has protective effect on diabetic nephropathy (DN). This study aims to demystify the mechanism of MET function in DN.

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