Abstract The purpose of the present study was to investigate the hormonal and biochemical profile of dromedary she-camels with multiple ovarian cysts (MOC). Seventeen she-camels suffering from MOC and 10 control animals were enrolled in this study. Blood samples were collected from all animals. Progesterone (P4), estradiol 17-β (E2), Testosterone, tri-iodothyronine (T3), Thyroxine (T4), glucose, total protein, albumin, total cholesterol, triglycerides, HDL, nitric oxide (NO), malondialdehyde (MDA) and glutathione peroxidase (GPX) levels were estimated in blood serum. Results revealed the presence of three or more large follicular ovarian cysts either on one (n = 6) or both ovaries (n = 11) of MOC cases with absence of any luteal structure. She-camels with multiple MOC had significantly (P ≤ 0.001) lower levels of P4 (0.24 ± 0.02 vs. 0.40 ± 0.03 ng/mL, respectively) and significantly higher levels of E2 and T3 (19.62 ± 0.62 vs. 13.74 ± 0.67 pg/mL, P ≤ 0.001 and 1.85 ± 0.09 vs. 1.44 ± 0.10 ng/mL, P ≤ 0.012, respectively) as compared with control. There were no significant differences between the two groups regarding testosterone and T4 levels (0.031 ± 0.002 vs. 0.026 ± 0.001 and 10.93 ± 0.24 vs. 10.17 ± 0.28 ng/mL, respectively). She-camels having MOC had significantly higher levels of glucose, cholesterol, triglycerides, HDL, total lipids and MDA and lower levels of GPX and NO as compared with control group. There were no significant differences between the two groups in levels of total proteins, albumin and globulin. In conclusion, the hormonal imbalances, metabolic disorders and oxidative stress are involved in the formation and/or persistence of multiple ovarian cysts in dromedary camels.

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受多发性卵巢囊肿影响的雌性单峰骆驼的激素和生化研究

摘要 本研究的目的是调查患有多发性卵巢囊肿 (MOC) 的单峰母骆驼的激素和生化特征。17 只患有 MOC 的母骆驼和 10 只对照动物参加了这项研究。从所有动物收集血样。孕酮 (P4)、雌二醇 17-β (E2)、睾酮、三碘甲状腺原氨酸 (T3)、甲状腺素 (T4)、葡萄糖、总蛋白、白蛋白、总胆固醇、甘油三酯、HDL、一氧化氮 (NO)、丙二醛 (MDA) ) 和谷胱甘肽过氧化物酶 (GPX) 水平在血清中被估计。结果显示，在没有任何黄体结构的 MOC 病例中，一个 (n = 6) 或两个卵巢 (n = 11) 上存在三个或更多大的卵泡性卵巢囊肿。具有多个 MOC 的母骆驼的 P4 水平显着（P ≤ 0.001）较低（0.24 ± 0.02 vs. 0.40 ± 0。03 ng/mL）和显着更高水平的 E2 和 T3（分别为 19.62 ± 0.62 与 13.74 ± 0.67 pg/mL，P ≤ 0.001 和 1.85 ± 0.09 与 1.44 ± 0.10 ng/mL，P ≤ 2）0。与对照相比。在睾酮和 T4 水平方面，两组之间没有显着差异（分别为 0.031 ± 0.002 对 0.026 ± 0.001 和 10.93 ± 0.24 对 10.17 ± 0.28 ng/mL）。与对照组相比，具有 MOC 的母骆驼具有显着更高水平的葡萄糖、胆固醇、甘油三酯、HDL、总脂质和 MDA 以及更低水平的 GPX 和 NO。两组间总蛋白、白蛋白和球蛋白水平无显着差异。总之，荷尔蒙失调，