Bladder cancer is the tenth most common cancer worldwide and has been associated with high mortality and morbidity. Although the treatment of bladder cancer is based on well-defined tumor classifications and gradings, patients still experience different clinical response. The heterogeneity of this disease calls for substantial research with more in-depth molecular characterization, with the hope of identifying new diagnostic and treatment options. In recent years, non-coding RNAs (ncRNAs), particularly, microRNAs (miRNAs), long non-coding RNA (lncRNAs), and circular RNAs (circRNAs) were found to be associated with bladder cancer occurrence and development. This review highlights the recent findings concerning ncRNAs and their relevance to the pathogenesis of bladder cancer. This may provide a foundation for developing highly specific diagnostic tools and more robust therapeutic strategies in the future.

中文翻译：

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膀胱癌中的非编码RNA。

膀胱癌是全球第十大最常见的癌症，与高死亡率和高发病率有关。尽管膀胱癌的治疗是基于明确的肿瘤分类和等级，但是患者仍然会经历不同的临床反应。这种疾病的异质性要求进行更深入的分子表征的大量研究，以期寻找新的诊断和治疗选择。近年来，发现非编码RNA（ncRNA），特别是microRNA（miRNA），长的非编码RNA（lncRNA）和环状RNA（circRNA）与膀胱癌的发生和发展有关。这篇综述强调了有关ncRNA及其与膀胱癌发病机制相关性的最新发现。