Like communities of people, communities of cells must continuously communicate to thrive. Polypeptide signaling molecules that act as mobile ligands are widely used by eukaryotic organisms to transmit information between cells to coordinate developmental processes and responses to environmental cues. In plants, the CLAVATA3/EMBRYO SURROUNDING REGION-RELATED (CLE) genes encode a large family of extracellular signaling peptides that stimulate receptor-mediated signal transduction cascades to modulate diverse developmental and physiological processes. This review highlights the emerging roles of Arabidopsis thaliana CLE peptide signaling pathways in shoot stem cell homeostasis and root xylem development, as well as in root protophloem cell differentiation, vascular cambium activity, and stomatal formation and closure.

像人社区一样，细胞社区必须不断地交流才能蓬勃发展。用作移动配体的多肽信号分子已被真核生物广泛用于在细胞之间传递信息，以协调发育过程和对环境线索的反应。在植物中，与CLAVATA3 / EMBRYO周围环境相关的基因（CLE）编码大量的细胞外信号肽，刺激受体介导的信号转导级联反应，从而调节各种发育和生理过程。本文综述了新兴角色一个拟南芥 拟南芥 茎干细胞稳态和根木质部发育以及根原皮细胞分化，血管形成层活性以及气孔形成和闭合中的CLE肽信号通路。